{"id":116819,"date":"2026-10-22T05:32:56","date_gmt":"2026-10-21T21:32:56","guid":{"rendered":"https:\/\/www.wsisp.com\/helps\/116819.html"},"modified":"2026-10-22T05:32:56","modified_gmt":"2026-10-21T21:32:56","slug":"nature-%e7%b3%bb%e5%88%97%e7%bb%bc%e8%bf%b0%ef%bd%9c%e6%8a%97%e5%be%ae%e7%94%9f%e7%89%a9%e8%80%90%e8%8d%af%e6%80%a7%e7%9a%84%e7%8e%af%e5%a2%83%e5%bd%b1%e5%93%8d%e3%80%81%e7%9b%91%e6%b5%8b%e4%b8%8e","status":"publish","type":"post","link":"https:\/\/www.wsisp.com\/helps\/116819.html","title":{"rendered":"Nature \u7cfb\u5217\u7efc\u8ff0\uff5c\u6297\u5fae\u751f\u7269\u8010\u836f\u6027\u7684\u73af\u5883\u5f71\u54cd\u3001\u76d1\u6d4b\u4e0e\u7f13\u89e3"},"content":{"rendered":"<p><img decoding=\"async\" src=\"https:\/\/www.wsisp.com\/helps\/wp-content\/uploads\/2026\/10\/20261021213252-6ad92f84d59f8.png\" alt=\"\" \/><\/p>\n<h3>\u6458\u8981<\/h3>\n<p>\u6297\u5fae\u751f\u7269\u8010\u836f\u6027&#xff08;antimicrobial resistance, AMR&#xff09;\u662f\u5b9e\u73b0\u8054\u5408\u56fd\u53ef\u6301\u7eed\u53d1\u5c55\u76ee\u6807\u7684\u91cd\u8981\u969c\u788d\u3002\u73af\u5883\u5728AMR\u7684\u4ea7\u751f\u4e0e\u4f20\u64ad\u8fc7\u7a0b\u4e2d\u5177\u6709\u5173\u952e\u4f5c\u7528\u3002\u672c\u7efc\u8ff0\u7cfb\u7edf\u603b\u7ed3\u5168\u7403\u73af\u5883\u4e2dAMR\u5206\u5e03\u683c\u5c40&#xff0c;\u5256\u6790\u5176\u4e3b\u8981\u6765\u6e90\u4e0e\u9a71\u52a8\u56e0\u7d20\u3002\u57fa\u4e8e\u5168\u7403\u73af\u5883\u5b8f\u57fa\u56e0\u7ec4\u5206\u6790&#xff0c;\u6c34\u4f53\u662f\u7f16\u7801AMR\u7684\u7ec6\u83cc\u9057\u4f20\u5143\u4ef6\u4e3b\u8981\u4f20\u64ad\u901a\u9053&#xff0c;\u5176\u4e2d\u6c61\u6c34\u8d21\u732e\u6700\u5927&#xff0c;\u5176\u6b21\u4e3a\u6de1\u6c34\u7cfb\u7edf&#xff0c;\u571f\u58e4\u4f5c\u7528\u76f8\u5bf9\u6709\u9650\u3002\u9274\u4e8e\u4e0d\u540c\u73af\u5883\u4ecb\u8d28\u4e2d\u5fae\u751f\u7269\u7ec4\u4e0e\u6297\u751f\u7d20\u8010\u836f\u57fa\u56e0&#xff08;antibiotic resistance gene, ARG&#xff09;\u7684\u590d\u6742\u6027&#xff0c;\u4f53\u7cfb\u5316\u76d1\u6d4b\u662f\u7406\u89e3AMR\u6f14\u5316\u4e0e\u6269\u6563\u7684\u524d\u63d0\u3002\u4e3a\u514b\u670d\u65e2\u6709\u73af\u5883AMR\u7814\u7a76\u7684\u65b9\u6cd5\u5f02\u8d28\u6027&#xff0c;\u4f5c\u8005\u63d0\u51fa\u57fa\u4e8e\u6807\u51c6\u5316\u5b8f\u57fa\u56e0\u7ec4\u7684\u6574\u5408\u76d1\u6d4b\u6846\u67b6&#xff1a;\u5728\u8d44\u6e90\u53d7\u9650\u6761\u4ef6\u4e0b\u91c7\u7528\u6700\u4f4e\u9650\u5ea6\u7b56\u7565\u83b7\u53d6\u57fa\u7840\u8010\u836f\u4fe1\u606f&#xff0c;\u5728\u8d44\u6e90\u5145\u8db3\u6761\u4ef6\u4e0b\u91c7\u7528\u7efc\u5408\u7b56\u7565\u5f00\u5c55\u6df1\u5ea6\u89e3\u6790\u3002\u8868\u5f81\u73af\u5883\u8010\u836f\u7ec4&#xff08;resistome&#xff09;\u53ef\u8bc6\u522b\u533a\u57df\u95ee\u9898\u5e76\u652f\u6491\u51cf\u7f13\u7b56\u7565\u8bbe\u8ba1\u3002\u4f5c\u8005\u4e3b\u5f20\u5c06\u7cfb\u7edf\u73af\u5883\u76d1\u6d4b\u7eb3\u5165AMR\u6cbb\u7406&#xff0c;\u4ee5\u9610\u660e\u6765\u6e90\u3001\u4f20\u64ad\u8def\u5f84\u5e76\u63a8\u52a8\u4e00\u4f53\u5316\u7ba1\u7406\u6269\u5bb9\u3002<\/p>\n<p>\u5173\u952e\u8bcd&#xff1a;\u6297\u5fae\u751f\u7269\u8010\u836f\u6027&#xff08;AMR&#xff09;&#xff1b;\u6297\u751f\u7d20\u8010\u836f\u57fa\u56e0&#xff08;ARG&#xff09;&#xff1b;\u73af\u5883\u8010\u836f\u7ec4&#xff08;resistome&#xff09;&#xff1b;\u5b8f\u57fa\u56e0\u7ec4\u5b66&#xff08;metagenomics&#xff09;&#xff1b;\u6c61\u6c34\u76d1\u6d4b&#xff1b;One Health&#xff08;\u540c\u4e00\u5065\u5eb7&#xff09;<\/p>\n<ul>\n<li>Li, L., Ding, J., Gillings, M. R., Fatta-Kassinos, D., Manaia, C. M., Berendonk, T. U., Blaser, M. J., Topp, E., &amp; Zhang, T. (2026). Environmental impacts, surveillance and mitigation of antimicrobial resistance. 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(EU) 2024\/3019&#xff09;\u8981\u6c42\u4e00\u5b9a\u89c4\u6a21\u4ee5\u4e0a\u6c61\u6c34\u5382\u5f00\u5c55AMR\u76d1\u6d4b&#xff0c;WHO\u4ea6\u53d1\u5e03\u5e9f\u6c34\u4e0e\u73af\u5883\u76d1\u6d4b\u6307\u5bfc\u3002\u4f46\u65b9\u6cd5\u4e0e\u6570\u636e\u6807\u51c6\u672a\u7edf\u4e00&#xff0c;\u9650\u5236\u4e86\u8de8\u533a\u57dfOne Health\u6bd4\u8f83\u3002<\/p>\n<h4>\u5e38\u89c4\u4e0e\u65b0\u5174\u65b9\u6cd5<\/h4>\n<p>\u57f9\u517b\u6cd5\u53ef\u83b7\u6307\u793a\u79cd\u5982\u5927\u80a0\u6746\u83cc&#xff08;Escherichia coli&#xff09;\u4e0e\u836f\u654f\u8868\u578b&#xff0c;\u4fbf\u4e8e\u548c\u4e34\u5e8a\u6bd4\u5bf9&#xff1b;\u4f46\u73af\u5883ARB\u591a\u4e0d\u53ef\u57f9\u517b\u6216\u5b58\u5728\u83cc\u682a\u5f02\u8d28&#xff0c;\u5355\u6307\u793a\u79cd\u4e0d\u8db3\u4ee5\u4ee3\u8868\u5168\u90e8ARG\u3002PCR\u53ef\u5feb\u901f\u68c0\u6d4b\u5df2\u77e5ARG&#xff0c;\u4f46\u53d7\u5f15\u7269\u8986\u76d6\u9650\u5236\u3002\u5b8f\u57fa\u56e0\u7ec4\u53ef\u65e0\u504f\u89e3\u6790\u7fa4\u843d\u3001ARG\u3001\u5bbf\u4e3b\u4e0e\u53ef\u79fb\u52a8\u5143\u4ef6&#xff0c;\u4f46\u77ed\u8bfb\u957f\u5e38\u96be\u4ee5\u7ec4\u88c5ARG\u5b8c\u6574\u9057\u4f20\u80cc\u666f&#xff1b;\u957f\u8bfb\u957f\u3001Hi-C proximity-ligation\u3001\u5355\u7ec6\u5305\u6d4b\u5e8f\u4e0e\u76ee\u6807\u6355\u83b7\u53ef\u8865\u5145\u5bbf\u4e3b\u5f52\u5c5e\u3001\u8d28\u7c92\u8fde\u9501\u4e0e\u4f4e\u9891\u53d8\u5f02&#xff0c;\u4f46\u6210\u672c\u4e0e\u8ba1\u7b97\u9700\u6c42\u8f83\u9ad8\u3002<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.wsisp.com\/helps\/wp-content\/uploads\/2026\/10\/20261021213254-6ad92f86d295e.png\" alt=\"\" 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L., Ding, J., Gillings, M. R., Fatta-Kassinos, D., Manaia, C. M., Berendonk, T. U., Blaser, M. J., Topp, E., &amp; Zhang, T. (2026). Environmental impacts, surveillance and mitigation of antimicrobial resistance. Nature Reviews Earth &amp; Environment. https:\/\/doi.org\/10.1038\/s43017-026-00837-4<\/li>\n<li>WHO. Wastewater and Environmental Surveillance Summary for Antimicrobial Resistance (2025). https:\/\/www.who.int\/<\/li>\n<li>WHO. Integrated Global Surveillance on ESBL-Producing E. coli Using a One Health Approach (2021). https:\/\/www.who.int\/<\/li>\n<li>European Union. Directive (EU) 2024\/3019 concerning Urban Wastewater Treatment (Recast). https:\/\/eur-lex.europa.eu\/<\/li>\n<li>GenBank database resources. https:\/\/www.ncbi.nlm.nih.gov\/genbank\/<\/li>\n<li>CARD resistance gene database. https:\/\/card.mcmaster.ca\/<\/li>\n<li>ResFinder antimicrobial resistance gene resources. https:\/\/genomicepidemiology.org\/services\/resfinder\/<\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>\u6458\u8981<br \/>\n\u6297\u5fae\u751f\u7269\u8010\u836f\u6027&#xff08;antimicrobial resistance, AMR&#xff09;\u662f\u5b9e\u73b0\u8054\u5408\u56fd\u53ef\u6301\u7eed\u53d1\u5c55\u76ee\u6807\u7684\u91cd\u8981\u969c\u788d\u3002\u73af\u5883\u5728AMR\u7684\u4ea7\u751f\u4e0e\u4f20\u64ad\u8fc7\u7a0b\u4e2d\u5177\u6709\u5173\u952e\u4f5c\u7528\u3002\u672c\u7efc\u8ff0\u7cfb\u7edf\u603b\u7ed3\u5168\u7403\u73af\u5883\u4e2dAMR\u5206\u5e03\u683c\u5c40&#xff0c;\u5256\u6790\u5176\u4e3b\u8981\u6765\u6e90\u4e0e\u9a71\u52a8\u56e0\u7d20\u3002\u57fa\u4e8e\u5168\u7403\u73af\u5883\u5b8f\u57fa\u56e0\u7ec4\u5206\u6790&#xff0c;\u6c34\u4f53\u662f\u7f16\u7801AMR\u7684\u7ec6\u83cc\u9057\u4f20\u5143\u4ef6\u4e3b\u8981\u4f20\u64ad\u901a\u9053&#xff0c;\u5176\u4e2d\u6c61\u6c34\u8d21\u732e\u6700\u5927&#xff0c;\u5176\u6b21\u4e3a\u6de1\u6c34\u7cfb\u7edf&#xff0c;\u571f\u58e4\u4f5c\u7528\u76f8\u5bf9\u6709\u9650\u3002\u9274\u4e8e\u4e0d\u540c\u73af\u5883\u4ecb\u8d28\u4e2d\u5fae\u751f\u7269\u7ec4\u4e0e\u6297<\/p>\n","protected":false},"author":2,"featured_media":116815,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[801],"topic":[],"class_list":["post-116819","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-server","tag-801"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.3 - 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