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decoding=\"async\" src=\"https:\/\/www.wsisp.com\/helps\/wp-content\/uploads\/2026\/10\/20261001144926-6abe72f69dd21.png\" alt=\"\" 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KD, et al. A practical solution to pseudoreplication bias in single-cell studies. Nat. Commun. 2021. \u3002\u56fe2\u4f7f\u7528\u5176Fig. 1&#xff0c;CC BY 4.0\u3002<\/li>\n<li>Zhang\u7b49. Integrative cfDNA profiling from low-pass whole-genome sequencing enables tissue-of-origin prediction in cancer. Mol. Biomed. 2026. \u3002\u56fe3\u3001\u56fe10\u4f7f\u7528\u5176Fig. 1\u3001Fig. 3&#xff0c;CC BY 4.0\u3002<\/li>\n<li>Moss J, et al. Comprehensive human cell-type methylation atlas reveals origins of circulating cell-free DNA in health and disease. Nat. Commun. 2018. \u3002\u56fe4\u4f7f\u7528\u5176Fig. 1&#xff0c;CC BY 4.0\u3002<\/li>\n<li>Stanley KE, et al. Cell type signatures in cell-free DNA fragmentation profiles reveal disease biology. Nat. Commun. 2024. \u3002\u56fe5\u3001\u56fe8\u4f7f\u7528\u5176Fig. 1\u3001Fig. 4&#xff0c;CC BY 4.0\u3002<\/li>\n<li>Berman\u7b49. Long-read sequencing identifies aberrant fragmentation patterns linked to elevated cell-free DNA levels in cancer. Genome Biol. 2026. \u3002\u56fe6\u4f7f\u7528\u5176Fig. 3&#xff0c;CC BY 4.0\u3002<\/li>\n<li>Xu\u7b49. Cell-free DNA fragmentomics for preeclampsia risk assessment. Nat. Commun. 2026. \u3002\u56fe7\u4f7f\u7528\u5176Fig. 1&#xff0c;CC BY 4.0\u3002<\/li>\n<li>He\u7b49. Development, characterization, and inter-laboratory validation of methylated human cell free DNA candidate reference materials. Clin. Epigenetics 2026. \u3002\u56fe9\u4f7f\u7528\u5176Fig. 4&#xff0c;CC BY 4.0\u3002<\/li>\n<li>Klein EA, et al. Clinical validation of a targeted methylation-based multi-cancer early detection test using an independent validation set. Ann. Oncol. 2021. PubMed\u3002<\/li>\n<li>Schrag D, et al. Blood-based tests for multicancer early detection (PATHFINDER): a prospective cohort study. Lancet. 2023. PMC\u5168\u6587\u3002<\/li>\n<li>Nabavizadeh\u7b49. Performance and safety of a multi-cancer early detection test: the PATHFINDER 2 study. Nat. Med. 2026. \u3002\u56fe11\u4f7f\u7528\u5176Fig. 2&#xff0c;CC BY 4.0\u3002<\/li>\n<li>Tie J, et al. Circulating Tumor DNA Analysis Guiding Adjuvant Therapy in Stage II Colon Cancer. N. Engl. J. 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