{"id":104419,"date":"2026-09-12T13:41:22","date_gmt":"2026-09-12T05:41:22","guid":{"rendered":"https:\/\/www.wsisp.com\/helps\/104419.html"},"modified":"2026-09-12T13:41:22","modified_gmt":"2026-09-12T05:41:22","slug":"%e5%90%ac%e8%af%b4%e4%bd%a0%e6%83%b3%e8%92%b8%e9%a6%8f%e6%88%91%ef%bc%9f","status":"publish","type":"post","link":"https:\/\/www.wsisp.com\/helps\/104419.html","title":{"rendered":"\u542c\u8bf4\u4f60\u60f3\u84b8\u998f\u6211\uff1f"},"content":{"rendered":"<h2>\u4e00\u3001\u84b8\u998f\u8fc7\u7a0b<\/h2>\n<p>\u5728\u8bc4\u8bba\u533a\u53d1\u73b0\u6709\u4eba\u60f3\u84b8\u998f\u6211&#xff1f;\u884c\u5427&#xff0c;\u7c89\u4e1d\u60f3\u8981&#xff0c;\u7c89\u4e1d\u5f97\u5230\u3002<\/p>\n<p><img decoding=\"async\" src=\"https:\/\/www.wsisp.com\/helps\/wp-content\/uploads\/2026\/09\/20260912054119-6aa4e5ff8b187.png\" alt=\"\u56fe\u7247\" \/><\/p>\n<p>\u5148\u770b\u4e0b\u7528\u84b8\u998f\u540e\u7684skills\u7684\u7ed8\u56fe\u6548\u679c&#xff1a;<\/p>\n<p><img decoding=\"async\" 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operator\">:<\/span> <span class=\"token punctuation\">[<\/span><span class=\"token punctuation\">]<\/span>  <span class=\"token comment\">\/\/ \u6700\u4f73\u5b9e\u8df5&#xff0c;\u8be5\u600e\u4e48\u505a<\/span><br \/>\n<span class=\"token punctuation\">}<\/span><br \/>\n\u53ea\u8f93\u51fa<span class=\"token constant\">JSON<\/span>&#xff0c;\u4e0d\u8981markdown\u89e3\u91ca\u3002<br \/>\n\u5bf9\u6bcf\u4e00\u4e2a\u5206\u7247\u8c03\u7528 DeepSeek&#xff0c;\u628a\u8fd4\u56de\u7684 <span class=\"token constant\">JSON<\/span> \u5168\u90e8\u4fdd\u5b58&#xff0c;\u5f97\u5230\u4e00\u4e2a\u77e5\u8bc6\u5e93\u5408\u96c6 sc_knowledge_base<span class=\"token punctuation\">.<\/span>json\u3002<\/p>\n<p>\u6b65\u9aa4\u4e8c<\/p>\n<p>\u6839\u636e\u4e0a\u4e00\u6b65\u751f\u6210\u7684sc_knowledge_base.json\u751f\u6210skills<\/p>\n<p>\u4f60\u73b0\u5728\u9700\u8981\u57fa\u4e8e\u4e0b\u9762\u7684\u5355\u7ec6\u80de\u751f\u4fe1\u7ed3\u6784\u5316\u77e5\u8bc6\u5e93&#xff0c;\u751f\u6210\u4e00\u4efd\u5b8c\u6574\u7b26\u5408Claude Code\u89c4\u8303\u7684 SKILL.md\u3002<br \/>\n\u76ee\u6807&#xff1a;\u5f53Claude Code\u505a\u5355\u7ec6\u80de\u6570\u636e\u5206\u6790\u4efb\u52a1\u65f6&#xff0c;\u81ea\u52a8\u9075\u5faaBiomamba\u751f\u4fe1\u57fa\u5730\u7684\u5b9e\u64cd\u7ecf\u9a8c\u3001\u6d41\u7a0b\u3001\u907f\u5751\u3001\u4ee3\u7801\u98ce\u683c\u3002<br \/>\n\u8981\u6c42&#xff1a;<br \/>\n1. \u5f00\u5934\u8bf4\u660eSkill\u7528\u9014&#xff1a;\u672cSkill\u4e3aBiomamba\u5355\u7ec6\u80de\u5206\u6790\u7ecf\u9a8c\u84b8\u998f&#xff0c;\u7528\u4e8e\u6307\u5bfcClaude Code\u5b8c\u6210\u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u5206\u6790\u3002<br \/>\n2. \u3010\u4efb\u52a1\u884c\u4e3a\u7ea6\u675f\u3011&#xff1a;Agent\u505a\u5355\u7ec6\u80de\u5206\u6790\u65f6\u56fa\u5b9a\u5206\u6790\u6d41\u7a0b\u987a\u5e8f&#xff1b;\u4f18\u5148\u4f7f\u7528Seurat\/Scanpy&#xff1b;\u4e25\u683c\u9075\u5faa\u77e5\u8bc6\u5e93\u91cc\u9762\u7684\u6700\u4f73\u5b9e\u8df5\u3002<br \/>\n3. \u3010\u4ee3\u7801\u8f93\u51fa\u7ea6\u675f\u3011&#xff1a;\u8f93\u51faR\/Python\u5355\u7ec6\u80de\u4ee3\u7801\u7684\u98ce\u683c&#xff0c;\u53c2\u8003\u77e5\u8bc6\u5e93code_pattern&#xff1b;\u4e0d\u8981\u8f93\u51fa\u8fc7\u65f6\u5199\u6cd5\u3002<br \/>\n4. \u3010\u5f3a\u5236\u68c0\u67e5\u6e05\u5355\u3011&#xff1a;\u6bcf\u5b8c\u6210\u4e00\u4e2a\u6b65\u9aa4&#xff0c;\u5fc5\u987b\u81ea\u67e5pitfall\u91cc\u9762\u7684\u5751\u70b9&#xff1b;\u9047\u5230\u62a5\u9519\u4f18\u5148\u53c2\u8003error_case\u3002<br \/>\n5. \u3010\u53c2\u6570\u7ea6\u675f\u3011&#xff1a;\u51fd\u6570\u8c03\u7528\u4f18\u5148\u4f7f\u7528param_suggest\u7ed9\u51fa\u7684\u63a8\u8350\u53c2\u6570&#xff0c;\u4e0d\u968f\u610f\u8bbe\u7f6e\u9ed8\u8ba4\u503c\u3002<br \/>\n6. \u3010\u5de5\u5177\u8c03\u7528\u7ea6\u675f\u3011&#xff1a;\u7ed3\u5408\u6211\u4eec\u5df2\u6709\u7684settings.json\u6743\u9650\u767d\u540d\u5355&#xff0c;\u4f18\u5148\u4f7f\u7528\u5141\u8bb8\u7684bash\u547d\u4ee4&#xff0c;\u4e0d\u89e6\u53d1\u591a\u4f59\u786e\u8ba4\u3002<br \/>\n7. \u3010\u53ef\u89c6\u5316\u4f18\u5316\u3011&#xff1a;\u6d89\u53ca\u5230uamp\u3001doheatmap\u3001vlnplot\u3001Dotplot\u7b49&#xff0c;\u8bf7\u6309\u7167Biomamba\u7684\u6539\u9020\u7cfb\u5217\u98ce\u683c\u8fdb\u884c\u7ed8\u5236\u3002<br \/>\n8. \u5982\u679c\u7528\u6237\u63d0\u95ee&#xff0c;\u4f18\u5148\u4f7f\u7528\u77e5\u8bc6\u5e93\u5185\u7ecf\u9a8c&#xff0c;\u77e5\u8bc6\u5e93\u6ca1\u6709\u7684\u518d\u4f7f\u7528\u901a\u7528\u516c\u5f00\u77e5\u8bc6\u3002<br \/>\n9. \u683c\u5f0f\u4e25\u683c\u4e3aSKILL.md&#xff0c;\u4f7f\u7528markdown\u6807\u9898\u3001\u5217\u8868&#xff0c;\u4e0d\u8981\u8f93\u51fajson\u3002<\/p>\n<p>\u8fd9\u6837\u4f60\u5c31\u5f97\u5230\u4e86\u8fd9\u6837\u4e00\u4efdskills&#xff0c;\u7406\u8bba\u4e0a\u4f60\u5c31\u84b8\u998f\u4e86Biomamba\u4e00\u90e8\u5206\u7684\u6280\u80fd&#xff0c;\u53ef\u4ee5\u968f\u65f6\u8ba9\u6211\u7ed9\u4f60\u5e72\u6d3b&#xff0c;\u7b97\u662f\u8ba9Biomamba\u8d5b\u535a\u6c38\u751f\u4e86&#xff0c;\u4e0d\u77e5\u9053\u5927\u5bb6\u6709\u6ca1\u6709\u770b\u8fc7\u9ed1\u955c\u3002<\/p>\n<p>biomamba_sc_distill\/<br \/>\n\u251c\u2500\u2500 manifest.json<br \/>\n\u251c\u2500\u2500 mcp<br \/>\n\u2502   \u2514\u2500\u2500 sc_kb_server.py<br \/>\n\u251c\u2500\u2500 merge.py<br \/>\n\u251c\u2500\u2500 out<br \/>\n\u2502   \u251c\u2500\u2500 0001.json<br \/>\n\u2502   \u251c\u2500\u2500 0002.json<br \/>\n\u2502   \u251c\u2500\u2500 0003.json<br \/>\n\u2502   \u251c\u2500\u2500 0004.json<br \/>\n\u2502   \u251c\u2500\u2500 0005.json<br \/>\n<span class=\"token punctuation\">..<\/span><span class=\"token punctuation\">..<\/span><span class=\"token punctuation\">..<\/span><span class=\"token punctuation\">..<\/span><span class=\"token punctuation\">..<\/span><span class=\"token punctuation\">..<\/span><span class=\"token punctuation\">..<\/span><span class=\"token punctuation\">..<\/span>.<br \/>\n\u2502   \u251c\u2500\u2500 0137.json<br \/>\n\u2502   \u2514\u2500\u2500 0138.json<br \/>\n\u251c\u2500\u2500 preprocess.py<br \/>\n\u251c\u2500\u2500 prompts<br \/>\n\u2502   \u2514\u2500\u2500 sc_analysis_prompt.md<br \/>\n\u251c\u2500\u2500 ref<br \/>\n\u2502   \u251c\u2500\u2500 jupyter<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 AI_module.ipynb<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 article.ipynb<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 cell_communication.ipynb<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 ChimericSeq\u9274\u5b9a\u5355\u7ec6\u80de\u4e0e\u7a7a\u8f6c\u6570\u636e\u4e2d\u7684\u75c5\u6bd2\u5d4c\u5408\u5e8f\u5217.ipynb<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 cnv.ipynb<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 fig1_py.ipynb<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 gene_co_expression_network.ipynb<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 pseudotime.ipynb<br \/>\n\u2502   \u2502   \u251c\u2500\u2500 reproduction.ipynb<br \/>\n\u2502   \u2502   \u2514\u2500\u2500 scanpy.ipynb<br \/>\n\u2502   \u2514\u2500\u2500 rmd<br \/>\n\u2502       \u251c\u2500\u2500 Autodock Vina\u5206\u5b50\u6279\u91cf\u5bf9\u63a5\u4e0e\u4eb2\u548c\u529b\u70ed\u56fe\u7ed8\u5236.rmd<br \/>\n\u2502       \u251c\u2500\u2500 beyondcell\u6d41\u7a0b.R<br \/>\n\u2502       \u251c\u2500\u2500 Biomamba\u751f\u4fe1\u57fa\u5730.\u5355\u7ec6\u80de\u6559\u7a0b.rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u300aCancercell\u300b\u5355\u7ec6\u80de\u63ed\u793a\u7ed3\u76f4\u80a0\u764c\u514d\u75ab\u6cbb\u7597\u4e2d\u7684T Cell\u54cd\u5e94\u52a8\u6001.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 Cellchat.Part1-Biomamba.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 citeSeq\u5b66\u4e60\u624b\u518c.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 ComplexHeatmap\u5b66\u4e60\u624b\u518c.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 CRC_PBMC\u590d\u5199.rmd<br \/>\n\u2502       \u251c\u2500\u2500 Dotplot\u6539\u9020.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 fastXXX_RapidXXX\u52a0\u901f\u4f60\u7684\u5355\u7ec6\u80de\u5206\u6790.rmd<br \/>\n\u2502       \u251c\u2500\u2500 ggplot2\u4e2d\u7684DIY.rmd<br \/>\n\u2502       \u251c\u2500\u2500 macrophage.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 monocle2-Biomamba-\u751f\u4fe1\u57fa\u5730.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 monocle2-\u62df\u65f6\u5e8f\u5206\u6790\u7cbe\u7b80\u7248.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 monocle\u7684\u4e0b\u6e38\u63a2\u7d22.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 Neutrophil.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 oncoPredict_\u65b9\u6cd5\u4e00.R<br \/>\n\u2502       \u251c\u2500\u2500 oncoPredict_\u65b9\u6cd5\u4e8c.R<br \/>\n\u2502       \u251c\u2500\u2500 scanpy\u5355\u7ec6\u80de\u6d41\u7a0b.Rmarkdown\u7f16\u8bd1\u7248\u672c.rmd<br \/>\n\u2502       \u251c\u2500\u2500 scATAC\u5b66\u4e60\u624b\u518c.rmd<br \/>\n\u2502       \u251c\u2500\u2500 SCENIC\u6d41\u7a0b.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 SCENIC\u8f6c\u5f55\u56e0\u5b50\u8c03\u63a7\u7f51\u7edc\u5206\u6790.rmd<br \/>\n\u2502       \u251c\u2500\u2500 scMeta.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 scMLnet\u591a\u5c42\u4fe1\u53f7\u7f51\u7edc\u6559\u7a0b.rmd<br \/>\n\u2502       \u251c\u2500\u2500 scRNA-Seq\u5b66\u4e60\u624b\u518c_Seurat_V5\u7248.rmd<br \/>\n\u2502       \u251c\u2500\u2500 scRNA-seq\u63ed\u793a\u4eba\u7ea4\u7ef4\u5316\u76ae\u80a4\u75c5\u4e2d\u7684\u6210\u7ea4\u7ef4\u7ec6\u80de\u5f02\u8d28\u6027\u548c\u95f4\u5145\u8d28\u6210\u7ea4\u7ef4\u7ec6\u80de\u589e\u52a0.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 scRNA-seq\u63ed\u793a\u5934\u9888\u764c\u65e9\u671f\u8f6c\u79fb\u8fc7\u7a0b\u4e2d\u6f5c\u5728\u7684\u514d\u75ab\u9003\u907f\u673a\u5236.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 scRNA-seq\u80bf\u7624\u7ec6\u80de\u836f\u654f\u5206\u6790.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 scRNA\u8054\u5408scATAC\u63ed\u793a\u80be\u810f\u7ec6\u80de\u5206\u5316\u7a0b\u5e8f\u548c\u75be\u75c5\u9776\u70b9.rmd<br \/>\n\u2502       \u251c\u2500\u2500 scTCR<span class=\"token operator\">&amp;<\/span>scBCR\u5b66\u4e60\u624b\u518c.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 scTenifoldKnk\u5355\u7ec6\u80de\u865a\u62df\u57fa\u56e0\u6572\u9664.rmd<br \/>\n\u2502       \u251c\u2500\u2500 SeekOne DD\u5355\u7ec6\u80deATAC&#043;RNA\u4e00\u80de\u53cc\u7ec4\u5b66_\u5b66\u4e60\u624b\u518c.rmd<br \/>\n\u2502       \u251c\u2500\u2500 SeekSpace_V2\u7115\u65b0\u4e0a\u7ebf.rmd<br \/>\n\u2502       \u251c\u2500\u2500 Seurat\u4e2d\u5982\u4f55\u8ba9\u7ec6\u80de\u542c\u4f60\u6307\u6325.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 Slingshot\u62df\u65f6\u5e8f\u5206\u6790\u5b66\u4e60\u624b\u518c.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 TCGA\u4e0e\u5355\u7ec6\u80de\u6570\u636e\u7684\u751f\u5b58\u5206\u6790\u4e0e\u9884\u540e\u5206\u6790\u5957\u8def\u5408\u96c6.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u5355\u6837\u672c\u5206\u6790.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u5355\u7ec6\u80deDoHeatmap\u6539\u9020.rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u5355\u7ec6\u80deFigure1\u7684\u5e38\u89c1\u56fe\u8868.rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u5355\u7ec6\u80deNMF\u975e\u8d1f\u77e9\u9635\u5206\u89e3\u964d\u7ef4\u53ca\u4e9a\u7fa4\u5206\u6790\u5e94\u7528.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u5355\u7ec6\u80de\u53bb\u6c61\u67d3\u5b66\u4e60\u624b\u518c.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u5355\u7ec6\u80de\u8f6c\u5f55\u7ec4\u5b66\u5bf9\u4ea7\u540e\u809d\u810f\u53d1\u80b2\u548c\u6210\u719f\u7684\u65f6\u95f4\u5206\u6790.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u53cc\u7ec6\u80de\u8fc7\u6ee4\u624b\u518c.rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u57fa\u56e0\u96c6\u8bc4\u5206\u65b9\u6cd5\u7684\u6a2a\u5411\u6bd4\u8f83.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u591a\u7ec4\u522b\u7ec6\u80de\u901a\u8baf.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u5feb\u901f\u4e0a\u624bSeurat_V5.rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u624b\u628a\u624b\u6559\u4f60\u505ascRNA-seq_\u57fa\u56e0\u5171\u8868\u8fbe\u7f51\u7edc\u5206\u6790\u5b66\u4e60\u624b\u518c.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 \u624b\u628a\u624b\u6559\u4f60\u505ascRNA-seq_\u62f7\u8d1d\u6570\u53d8\u5f02\u4e13\u9898.Rmd<br \/>\n\u2502       \u251c\u2500\u2500 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